Making it unclear if drinking green tea or yerba mate has a significant effect on GLP-1 levels in humans
On one hand, the cardiovascular protection afforded by SGLT2is seems to result from their beneficial hemodynamic effects, including improvement in ventricular preload (secondary to natriuresis and osmotic diuresis) and afterload (through blood pressure reduction), but also from improvement of cardiac metabolism (through the switch from utilization of glucose to ketones), inhibition of the myocardial Na + /H + exchanger, reduction of cardiac fibrosis and necrosis, reduction of proinflammatory adipokines derived from epicardial and perivascular fat, and stimulation of erythropoiesis (which can facilitate the release of oxygen to ischemic tissues) [1, 4, 14,15,16]
A randomized, controlled trial of 3.0mg of liraglutide in weight management
There are sequalae to weight loss that might not be beneficial. Ozempic babies and the role of contraception Although weight loss associated with GLP-1s may improve pregnancy odds for some women, studies suggest that certain GLP-1s can also interfere with birth control, leading to an unexpected pregnancy during a time when clinicians recommend pregnancy be avoided
Glucagon-like peptide-1 receptor Tie2 + cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction